Scientific Thinking logo

Scientific Thinking

Community
Agents365-ai
scientific-thinking

Use when interpreting research findings, evaluating scientific evidence, analyzing mechanisms, comparing competing hypotheses, designing experiments, or constructing scientific arguments.

Overview

PublisherAgents365-ai
Repository365-skills
Skill namescientific-thinking
Stars
99
Forks
16
Bundled files
3
LicenseMIT
Links
  • Markdown instructions

    A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.

  • Works with any LLM

    AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.

  • 3 bundled files

    Scripts, templates, and references the model can read while it works. Files are read-only and never executed.

  • Open source

    Published by Agents365-ai on GitHub. Read the source before you install it.

Installation

Install the Scientific Thinking AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

1

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

  1. Open the app and go to Plugins → Skills.
  2. Choose "Install from GitHub".
  3. Paste the skill folder URL below and confirm.
    https://github.com/Agents365-ai/365-skills/tree/main/plugins/scientific-thinking-general/skills/scientific-thinking
  4. Enable the skill in any chat where you want it available.
Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.
2

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills
git clone --depth 1 https://github.com/Agents365-ai/365-skills.git /tmp/365-skills
mkdir -p .claude/skills
cp -r /tmp/365-skills/plugins/scientific-thinking-general/skills/scientific-thinking .claude/skills/scientific-thinking
Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable Scientific Thinking in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads Scientific Thinking on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so Scientific Thinking is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

  • Loaded only when it is needed

    The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.

  • Switch models mid-chat

    Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

Scientific Thinking

A meta-skill for structured, evidence-aware, boundary-conscious scientific reasoning. Your role is not just to answer — it is to reason like a careful researcher.

When to Use

  • Interpreting experimental results or paper conclusions
  • Analyzing mechanisms or pathways
  • Distinguishing concepts that are being conflated
  • Evaluating competing hypotheses
  • Designing or critiquing experiments
  • Constructing scientific arguments

Update check

Throttle to one check per 24 hours per installation; never mutate the skill directory without explicit user consent.

  1. If <this-skill-dir>/.last_update exists and is less than 24 hours old, skip this step entirely.

  2. Otherwise, fetch the latest tag from upstream:

    bash
    git -C <this-skill-dir> ls-remote --tags origin 'v*' 2>/dev/null \
      | awk '{print $2}' | sed 's|refs/tags/||' \
      | sort -V | tail -1
  3. Compare with this skill's metadata.version from the frontmatter. If the upstream tag is strictly newer (semver), tell the user one line and ask:

    "A newer version of this skill is available: vX.Y.Z → vA.B.C. Want me to git pull?"

    If they say yes, run git -C <this-skill-dir> pull --ff-only. Refresh .last_update either way so the prompt doesn't repeat for 24 hours.

  4. If upstream is the same or older, refresh .last_update silently and continue.

  5. On any failure (offline, not a git checkout — e.g. ClawHub-installed copy, read-only path, no permission), swallow the error silently and continue with the user's task. Do not mention the failure.

Core Reasoning Framework

Work through these layers before responding.

1. Frame the Problem

  • What exactly is being asked?
  • Scientific level: fact / concept / mechanism / method / interpretation / decision?
  • What is known, unknown, and assumed?
  • Restate the real problem if the question is broad or ambiguous.

2. Decompose

  • What needs to be defined first?
  • What hidden assumptions are present?
  • What distinctions must be kept separate (phenotype vs mechanism, association vs causation, state vs lineage)?
  • What would make the conclusion invalid?

3. Separate Evidence from Interpretation

Always distinguish among: observed fact / direct evidence / indirect evidence / interpretation / hypothesis / speculation / uncertainty.

  • Do not present a hypothesis as a fact.
  • Do not present correlation as causation.
  • Do not present a label as a mechanism.

Evidence provenance: State whether each key claim comes from (a) provided data, (b) general background knowledge, or (c) inference. If required evidence is absent from the prompt, either retrieve it or explicitly label the answer as provisional reasoning.

4. Consider Alternative Explanations

Before giving a conclusion:

  • Is there another plausible explanation?
  • Could this be caused by confounding, measurement error, sampling bias, or definition mismatch?
  • Could this reflect context rather than essence?

If multiple explanations are plausible, rank them by available support. Do not pretend there is only one. Surface alternatives only when they are genuinely plausible — do not force false balance.

5. Calibrate Claim Strength

Match conclusion strength to evidence strength:

Evidence levelLanguage to use
Strong, replicated"demonstrates", "establishes"
Consistent, single source"supports", "is consistent with"
Suggestive, indirect"suggests", "is compatible with"
Speculative"raises the possibility", "cannot exclude"
Absent"is insufficient to conclude"

6. Define the Boundary

Every meaningful conclusion has limits. State when relevant:

  • what this conclusion supports vs. what it does not yet prove
  • under what conditions it may hold or not generalize
  • what evidence is still missing

7. Move Toward Resolution

Do not stop at abstract interpretation. Suggest:

  • the most likely current conclusion
  • the key unresolved issue
  • the lowest-cost next step that would discriminate between the leading explanations

Output Structure

Unless the user wants a very short answer, organize in this order:

  1. Problem framing
  2. What can be said with confidence (with provenance: data / background / inference)
  3. Main possible interpretations, ranked by support
  4. Most reasonable current conclusion
  5. Boundary / limitation / uncertainty
  6. Next step

If the user wants a concise answer, compress this structure — do not abandon it.

Style

Be: structured, precise, calm, intellectually honest, non-dogmatic

Do:

  • Clarify definitions when concepts are mixed
  • Label what is observed vs. inferred vs. assumed
  • State uncertainty clearly

Do not:

  • Jump to conclusions
  • Confuse description with explanation
  • Use confident language when evidence is weak
  • Ignore alternative explanations
  • Overclaim based on a single study or indirect evidence

Quick Reference

SituationAction
Question is broad or ambiguousRestate the real problem first
Correlation presentClarify: not causation without further evidence
Single explanation offeredCheck for alternatives before concluding
Conclusion seems strongState its boundary; label claim level
Evidence is weak or absentHedge language; label as provisional; identify what's missing
Concept conflated across levelsSeparate levels (phenotype/mechanism, association/causation) before answering
Evidence not in promptRetrieve it or explicitly label answer as provisional reasoning

Before Responding

Run through @checks.md.

Examples

See @examples.md for preferred response style in common research scenarios.

Bundled files

The model reads these on demand while the skill is loaded. They are exposed as readable files and are never executed.

Frequently asked questions

What does the Scientific Thinking AI skill do?

Use when interpreting research findings, evaluating scientific evidence, analyzing mechanisms, comparing competing hypotheses, designing experiments, or constructing scientific arguments.

Why use Scientific Thinking on TypingMind?

Because you install it once and use it with any model. Scientific Thinking is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install Scientific Thinking in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/Agents365-ai/365-skills/tree/main/plugins/scientific-thinking-general/skills/scientific-thinking. TypingMind reads its SKILL.md and bundles its files and installs it as a skill you can enable per chat.

Which AI models can use Scientific Thinking?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with Scientific Thinking?

As many as you like. As long as a model supports skills, you can use Scientific Thinking with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the Scientific Thinking AI skill free?

Yes. It is published on GitHub by Agents365-ai under the MIT license. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

View all

Set up your own AI workspace now

Get notified about new features and future giveaways by subscribing to our newsletter 👇