Hpa Expression Context logo

Hpa Expression Context

Organization
ai4protein
hpa_expression_context

Human Protein Atlas expression and localization via VenusFactory download tools. Use when the user needs tissue expression, subcellular location, single-cell type, blood expression, or protein summary by gene symbol for therapeutic/target context. Do NOT use for mouse/non-human expression atlases or PPI networks (string_database).

Overview

Publisherai4protein
RepositoryVenusFactory2
Skill namehpa_expression_context
Stars
255
Forks
37
Bundled files
Instructions only
LicenseUnknown
Links
  • Markdown instructions

    A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.

  • Works with any LLM

    AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.

  • Self-contained

    Everything the model needs lives in the instructions — no extra files to sync.

  • Open source

    Published by ai4protein on GitHub. Read the source before you install it.

Installation

Install the Hpa Expression Context AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

1

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

  1. Open the app and go to Plugins → Skills.
  2. Choose "Install from GitHub".
  3. Paste the skill folder URL below and confirm.
    https://github.com/ai4protein/VenusFactory2/tree/main/src/agent/skills/hpa_expression_context
  4. Enable the skill in any chat where you want it available.
Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.
2

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills
git clone --depth 1 https://github.com/ai4protein/VenusFactory2.git /tmp/VenusFactory2
mkdir -p .claude/skills
cp -r /tmp/VenusFactory2/src/agent/skills/hpa_expression_context .claude/skills/hpa_expression_context
Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable Hpa Expression Context in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads Hpa Expression Context on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so Hpa Expression Context is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

  • Loaded only when it is needed

    The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.

  • Switch models mid-chat

    Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

HPA Expression Context

Overview

Downloads Human Protein Atlas JSON/TSV-style payloads for a human gene symbol (e.g. TP53, EGFR). Always set a session-scoped out_path.

Project Tools (VenusFactory2)

ToolPurpose
download_hpa_protein_by_geneProtein summary / atlas entry
download_hpa_subcellular_location_by_geneSubcellular localization
download_hpa_tissue_expression_by_geneTissue expression ranks
download_hpa_single_cell_type_by_geneSingle-cell type expression
download_hpa_blood_expression_by_geneBlood / immune context

Args pattern: gene_name, out_path.

Workflow

  1. Confirm human gene symbol (map via UniProt / NCBI Gene if needed).
  2. Fetch tissue + subcellular (minimum useful pair).
  3. Optional single-cell / blood for immunology or circulating targets.
  4. Figure: bar chart of top tissues (nature_figure if publication).

When NOT to use

  • Non-human organisms → other databases / literature
  • Interaction partners → string_database
  • Domain architecture → interpro_domain_annotation

Common mistakes

  • Using UniProt accession as gene_name without checking HPA expects a gene symbol
  • Skipping tissue figure after download (CB policy expects a plot for expression tables)

Frequently asked questions

What does the Hpa Expression Context AI skill do?

Human Protein Atlas expression and localization via VenusFactory download tools. Use when the user needs tissue expression, subcellular location, single-cell type, blood expression, or protein summary by gene symbol for therapeutic/target context. Do NOT use for mouse/non-human expression atlases or PPI networks (string_database).

Why use Hpa Expression Context on TypingMind?

Because you install it once and use it with any model. Hpa Expression Context is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install Hpa Expression Context in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/ai4protein/VenusFactory2/tree/main/src/agent/skills/hpa_expression_context. TypingMind reads its SKILL.md and installs it as a skill you can enable per chat.

Which AI models can use Hpa Expression Context?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with Hpa Expression Context?

As many as you like. As long as a model supports skills, you can use Hpa Expression Context with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the Hpa Expression Context AI skill free?

Yes. It is published on GitHub by ai4protein under the Unknown license. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

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