Blast Search

Community

BioTender-max

blast-search

Run BLAST sequence similarity searches. Use when the user asks to BLAST a sequence, find similar sequences, identify a gene/protein, or do homology search. Triggers on "blast", "sequence similarity", "homology", "identify sequence".

Overview

Publisher	BioTender-max
Repository	`awesome-bio-agent-skills`
Skill name	`blast-search`
Stars	204
Forks	36
Bundled files	Instructions only
Links	Skill source Repository Homepage

Markdown instructions
A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.
Works with any LLM
AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.
Self-contained
Everything the model needs lives in the instructions — no extra files to sync.
Open source
Published by BioTender-max on GitHub. Read the source before you install it.

Installation

Install the Blast Search AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

Open the app and go to Plugins → Skills.
Choose "Install from GitHub".
Paste the skill folder URL below and confirm.
https://github.com/BioTender-max/awesome-bio-agent-skills/tree/main/skills/bioclaw/blast-search
Enable the skill in any chat where you want it available.

Store

Installed

Skills

Add skills

Import one or more skills from a public GitHub folder or a local .skill or .zip archive, or SKILL.md file.

From GitHub URLFrom .skill, .zip, or SKILL.md

GitHub repo or folder

https://github.com/BioTender-max/awesome-bio-agent-skills/tree/main/skills/bioclaw/blast-search

Points to a single skill folder, or any folder that contains multiple skills. Public repos only.

CancelContinue

Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills

git clone --depth 1 https://github.com/BioTender-max/awesome-bio-agent-skills.git /tmp/awesome-bio-agent-skills
mkdir -p .claude/skills
cp -r /tmp/awesome-bio-agent-skills/skills/bioclaw/blast-search .claude/skills/blast-search

Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable Blast Search in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads Blast Search on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so Blast Search is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

Loaded only when it is needed
The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.
Switch models mid-chat
Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

BLAST Search

Run NCBI BLAST+ searches inside the BioClaw container.

When to Use

User provides a DNA/RNA/protein sequence and wants to find similar sequences
User asks to identify an unknown sequence
User wants to check sequence conservation across species

How to Execute

1. Determine BLAST program

Input	Database	Program
Nucleotide query	Nucleotide DB	`blastn`
Protein query	Protein DB	`blastp`
Nucleotide query	Protein DB	`blastx`
Protein query	Nucleotide DB	`tblastn`

2. For local BLAST (sequences provided by user)

bash
# Create query file
cat > /tmp/query.fa << 'EOF'
>query_sequence
ATGCGATCGATCGATCG...
EOF

# Create subject file (if user provides reference)
cat > /tmp/subject.fa << 'EOF'
>reference
ATGCGATCGATCGATCG...
EOF

# Run BLAST
blastn -query /tmp/query.fa -subject /tmp/subject.fa -outfmt 6 -evalue 1e-5

3. For remote BLAST (against NCBI databases)

Use BioPython's NCBIWWW module:

python
from Bio.Blast import NCBIWWW, NCBIXML
from Bio import SeqIO

# Read sequence
sequence = "ATGCGATCGATCGATCG..."

# Run remote BLAST
result_handle = NCBIWWW.qblast("blastn", "nt", sequence)
blast_records = NCBIXML.parse(result_handle)

for record in blast_records:
    for alignment in record.alignments[:10]:
        print(f"Title: {alignment.title}")
        for hsp in alignment.hsps:
            print(f"  Score: {hsp.score}, E-value: {hsp.expect}")
            print(f"  Identity: {hsp.identities}/{hsp.align_length} ({hsp.identities/hsp.align_length*100:.1f}%)")

4. Output format

Present results in a clear table:


*BLAST Results (top 10 hits)*

• Hit 1: Homo sapiens TP53 gene (98.5% identity, E=1e-45)
• Hit 2: Mus musculus Trp53 gene (89.2% identity, E=1e-38)
...

5. Follow-up suggestions

After showing results, suggest:

Multiple sequence alignment of top hits
Phylogenetic analysis
Domain/motif analysis of the query
Structural comparison if protein

Frequently asked questions

What does the Blast Search AI skill do?

Why use Blast Search on TypingMind?

Because you install it once and use it with any model. Blast Search is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install Blast Search in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/BioTender-max/awesome-bio-agent-skills/tree/main/skills/bioclaw/blast-search. TypingMind reads its SKILL.md and installs it as a skill you can enable per chat.

Which AI models can use Blast Search?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with Blast Search?

As many as you like. As long as a model supports skills, you can use Blast Search with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the Blast Search AI skill free?

It is published on GitHub by BioTender-max. Check the repository for licensing terms. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

View all

Deslop

openclaw

OrganizationPopular

Diff-scoped AI-slop cleanup pass: strip comment slop, defensive-check slop, type-laundering, and style drift from the current branch diff before autoreview.

Discord Clawd

Use to talk to the Discord-backed OpenClaw agent/session; not for archive search.

Discrawl

Discord archive: search, sync freshness, DMs, summaries, TUI, repo/release work.

Gitcrawl

GitHub archive: issue/PR search, sync freshness, duplicate clusters, current GitHub handoff, and Gitcrawl repo work.

Overview

Installation

Install in TypingMind

Install in another agent

Use it in TypingMind

Works with any AI model

Skill instructions

BLAST Search

When to Use

How to Execute

1. Determine BLAST program

2. For local BLAST (sequences provided by user)

3. For remote BLAST (against NCBI databases)

4. Output format

5. Follow-up suggestions

Frequently asked questions

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