16 DGIdb

Community

QSong-github

16_DGIdb

Query the DGIdb (Drug-Gene Interaction Database) for drug-gene interactions, gene druggability categories, and drug target information. Use whenever the user asks about drug targets, druggable genes, gene-drug interactions, or wants to look up any entity (gene name, drug name, druggability category) in DGIdb.

Overview

Publisher	QSong-github
Repository	`DrugClaw`
Skill name	`16_DGIdb`
Stars	118
Forks	3
Bundled files	4
Links	Skill source Repository Homepage

Markdown instructions
A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.
Works with any LLM
AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.
4 bundled files
Scripts, templates, and references the model can read while it works. Files are read-only and never executed.
Open source
Published by QSong-github on GitHub. Read the source before you install it.

Installation

Install the 16 DGIdb AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

Open the app and go to Plugins → Skills.
Choose "Install from GitHub".
Paste the skill folder URL below and confirm.
https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/dgidb
Enable the skill in any chat where you want it available.

Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills

git clone --depth 1 https://github.com/QSong-github/DrugClaw.git /tmp/DrugClaw
mkdir -p .claude/skills
cp -r /tmp/DrugClaw/skills/dti/dgidb .claude/skills/16_DGIdb

Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable 16 DGIdb in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads 16 DGIdb on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so 16 DGIdb is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

Loaded only when it is needed
The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.
Switch models mid-chat
Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

DGIdb Query Skill

Search DGIdb records by any entity. Auto-detects type by naming convention:

Input Pattern	Detected As	Example
ALL-CAPS ≤15 chars	Gene	`EGFR`, `BRAF`, `TP53`
Known category keyword	Druggability category	`clinically actionable`, `kinase`
Anything else	Drug	`imatinib`, `erlotinib`

Supported category keywords: clinically actionable, drug resistance, druggable genome, tumor suppressor, transcription factor, kinase, g protein coupled receptor, hormone activity, ion channel, protease, dna repair.

API

Function	Input	Returns
`search(entity)`	single entity string	`list[dict]`
`search_batch(entities)`	list of entity strings	`dict[str, list[dict]]`
`summarize(results, entity)`	result list + label	compact text for LLM
`to_json(results)`	result list	`list[dict]` (passthrough)

Key Fields

Gene result: name, long_name, categories, interaction_count, interactions[] (each with drug, drug_concept_id, score, types, directionality, attributes, pmids, sources).

Drug result: name, concept_id, approval_ratings, interaction_count, interactions[] (each with gene, gene_long_name, score, types, directionality, attributes, pmids, sources).

Category result: category, gene_count, genes[] (each with name, long_name).

Usage

See if __name__ == "__main__" block in 16_DGIdb.py for runnable examples covering: single gene, single drug, category, batch (mixed types), and JSON output.

Data Source

Database: DGIdb v5.0 — Drug-Gene Interaction Database
Endpoint: https://dgidb.org/api/graphql (GraphQL, no API key)
Coverage: 40+ source databases, ~100 k drug-gene interactions
Paper: Freshour et al., Nucleic Acids Res. 2024; 52(D1):D1227-D1235. DOI: 10.1093/nar/gkac1046

Bundled files

The model reads these on demand while the skill is loaded. They are exposed as readable files and are never executed.

Frequently asked questions

What does the 16 DGIdb AI skill do?

Why use 16 DGIdb on TypingMind?

Because you install it once and use it with any model. 16 DGIdb is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install 16 DGIdb in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/dgidb. TypingMind reads its SKILL.md and bundles its files and installs it as a skill you can enable per chat.

Which AI models can use 16 DGIdb?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with 16 DGIdb?

As many as you like. As long as a model supports skills, you can use 16 DGIdb with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the 16 DGIdb AI skill free?

It is published on GitHub by QSong-github. Check the repository for licensing terms. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

View all

Control Ui E2e

openclaw

OrganizationPopular

Use when designing, testing, fixing, or extending the OpenClaw Control UI GUI, including UI stress-test galleries with feedback inputs, Vitest + Playwright end-to-end checks, mocked Gateway flows,…

Deslop

Diff-scoped AI-slop cleanup pass: strip comment slop, defensive-check slop, type-laundering, and style drift from the current branch diff before autoreview.

Discord Clawd

Use to talk to the Discord-backed OpenClaw agent/session; not for archive search.

Discord User Post

Post an approved message as the logged-in Discord user through the Discord desktop app. Use for release announcements or other direct user-authored Discord posts; not for OpenClaw channel sends, bots,…

Overview

Installation

Install in TypingMind

Install in another agent

Use it in TypingMind

Works with any AI model

Skill instructions

DGIdb Query Skill

API

Key Fields

Usage

Data Source

Bundled files

Frequently asked questions

Related AI Skills

Set up your own AI workspace now