Iuphar Pharmacology

Community

QSong-github

iuphar-pharmacology

Query the IUPHAR/BPS Guide to Pharmacology REST API for drug targets, ligands (drugs/compounds), and their interactions. Use whenever the user asks about pharmacological targets, receptor–ligand relationships, drug mechanisms of action, or wants to look up any drug or target name in IUPHAR. Supports single entity or batch queries. No API key required.

Overview

Publisher	QSong-github
Repository	`DrugClaw`
Skill name	`iuphar-pharmacology`
Stars	118
Forks	3
Bundled files	4
Links	Skill source Repository Homepage

Markdown instructions
A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.
Works with any LLM
AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.
4 bundled files
Scripts, templates, and references the model can read while it works. Files are read-only and never executed.
Open source
Published by QSong-github on GitHub. Read the source before you install it.

Installation

Install the Iuphar Pharmacology AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

Open the app and go to Plugins → Skills.
Choose "Install from GitHub".
Paste the skill folder URL below and confirm.
https://github.com/QSong-github/DrugClaw/tree/main/skills/drug_knowledgebase/iuphar
Enable the skill in any chat where you want it available.

Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills

git clone --depth 1 https://github.com/QSong-github/DrugClaw.git /tmp/DrugClaw
mkdir -p .claude/skills
cp -r /tmp/DrugClaw/skills/drug_knowledgebase/iuphar .claude/skills/iuphar-pharmacology

Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable Iuphar Pharmacology in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads Iuphar Pharmacology on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so Iuphar Pharmacology is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

Loaded only when it is needed
The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.
Switch models mid-chat
Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

IUPHAR/BPS Guide to Pharmacology Skill

Query the expert-curated IUPHAR database for ligands (drugs/compounds), targets (receptors/enzymes/channels), and ligand–target interactions.

Source: https://www.guidetopharmacology.org/
API docs: https://www.guidetopharmacology.org/webServices.jsp
Auth: None (open access)

Entity auto-detection

query_entity(name) tries ligand search first; if no hits, falls back to target search.

Input example	Detected as	What you get
`morphine`	ligand	ligandId, type, approved status, INN …
`5-HT1A receptor`	target	targetId, type, gene IDs, family IDs …
`GABA receptor`	target	target info + top 10 ligand–target interactions

API

Function	Input	Returns
`query_entity(name)`	single entity string	dict with `entity`, `type`, `results`, `interactions`
`query_entities(names)`	list of entity strings	`{name: result_dict}`
`summarize(result)`	output of `query_entity`	concise human-readable text
`search_ligand(name)`	drug/compound name	list of ligand dicts
`get_ligand(id)`	numeric ligand ID	full ligand detail dict
`search_target(name)`	target name	list of target dicts
`get_target(id)`	numeric target ID	full target detail dict
`get_interactions(target_id)`	numeric target ID	list of interaction dicts

Usage

python
from importlib.util import spec_from_file_location, module_from_spec
spec = spec_from_file_location("iuphar", "<path>/13_IUPHAR_BPS_Guide_to_Pharmacology.py")
iuphar = module_from_spec(spec); spec.loader.exec_module(iuphar)

# Single query
r = iuphar.query_entity("morphine")
print(iuphar.summarize(r))

# Batch query
results = iuphar.query_entities(["aspirin", "5-HT1A receptor"])
for name, res in results.items():
    print(iuphar.summarize(res))

See if __name__ == "__main__" block in the .py file for more runnable examples (single ligand, single target, batch, direct ID lookup).

Key fields returned

Ligand: ligandId, name, type, approved, inn, species

Target: targetId, name, abbreviation, type, familyIds, geneIds

Interaction: ligandId, targetId, action, affinityRange, affinityType, endogenous, species

Bundled files

The model reads these on demand while the skill is loaded. They are exposed as readable files and are never executed.

Frequently asked questions

What does the Iuphar Pharmacology AI skill do?

Why use Iuphar Pharmacology on TypingMind?

Because you install it once and use it with any model. Iuphar Pharmacology is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install Iuphar Pharmacology in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/QSong-github/DrugClaw/tree/main/skills/drug_knowledgebase/iuphar. TypingMind reads its SKILL.md and bundles its files and installs it as a skill you can enable per chat.

Which AI models can use Iuphar Pharmacology?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with Iuphar Pharmacology?

As many as you like. As long as a model supports skills, you can use Iuphar Pharmacology with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the Iuphar Pharmacology AI skill free?

It is published on GitHub by QSong-github. Check the repository for licensing terms. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

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Overview

Installation

Install in TypingMind

Install in another agent

Use it in TypingMind

Works with any AI model

Skill instructions

IUPHAR/BPS Guide to Pharmacology Skill

Entity auto-detection

API

Usage

Key fields returned

Bundled files

Frequently asked questions

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