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Stitch Query

Community
QSong-github
stitch-query

Query the STITCH chemical-protein interaction database. Use whenever the user asks about chemical-protein interactions, drug-target binding, compound action modes, or wants to look up any entity (chemical name, STITCH CID, STRING protein ID) in STITCH.

Overview

PublisherQSong-github
RepositoryDrugClaw
Skill namestitch-query
Stars
118
Forks
3
Bundled files
4
Links
  • Markdown instructions

    A SKILL.md file the model loads on demand, so it only costs tokens when a request actually matches.

  • Works with any LLM

    AI skills are plain Markdown, not provider-specific code, so this works with GPT, Claude, Gemini, Grok, or a local model.

  • 4 bundled files

    Scripts, templates, and references the model can read while it works. Files are read-only and never executed.

  • Open source

    Published by QSong-github on GitHub. Read the source before you install it.

Installation

Install the Stitch Query AI skill in TypingMind to use it with any LLM, or drop it into another agent that reads SKILL.md.

1

Install in TypingMind

TypingMind installs a skill straight from its GitHub folder — it reads SKILL.md, bundles the resource files, and stores the result locally.

  1. Open the app and go to Plugins → Skills.
  2. Choose "Install from GitHub".
  3. Paste the skill folder URL below and confirm.
    https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/stitch
  4. Enable the skill in any chat where you want it available.
Plugins → Skills → Add skill → From GitHub URL, then paste the folder URL and press Continue.
2

Install in another agent

Any agent that reads the Agent Skills format can use this skill — copy the folder into that agent's skills directory.

Claude Code — .claude/skills
git clone --depth 1 https://github.com/QSong-github/DrugClaw.git /tmp/DrugClaw
mkdir -p .claude/skills
cp -r /tmp/DrugClaw/skills/dti/stitch .claude/skills/stitch-query
Restart Claude Code after copying so it picks up the new skill.

Use it in TypingMind

Enable Stitch Query in any TypingMind chat and the model takes it from there. Its name and description sit in the system prompt, and the moment a request matches, the model loads the full instructions itself — you never invoke it by hand, and it costs no tokens until it is actually used.

The model loads Stitch Query on its own as soon as a request matches it.

Works with any AI model

AI skills are plain Markdown instructions rather than provider-specific code, so Stitch Query is not tied to the model it was written for. Install it once in TypingMind and use it with GPT-5, Claude, Gemini, Grok, DeepSeek, Mistral, Llama, or a local model you run yourself — all on your own API keys.

  • Loaded only when it is needed

    The system prompt carries just the name and description. The instructions are fetched on the first matching request, so an idle skill costs nothing.

  • Switch models mid-chat

    Because the skill is instructions rather than code, changing model does not break it — the next model reads the same SKILL.md.

Skill instructions

This is the SKILL.md content the model loads. Read it before installing — a skill is instructions your model will follow.

STITCH Query Skill

Search STITCH for chemical–protein interactions via REST API. Auto-detects input type:

Input PatternDetected AsExample
CIDm00002244 / CIDs00002244STITCH chemical IDdirect lookup
9606.ENSP00000352121STRING protein IDdirect lookup
anything elsefree textresolved via /resolve first

API

FunctionInputReturns
resolve(name, species)chemical / protein namelist[dict] with stringId, preferredName
resolve_batch(names, species)list of nameslist[dict] (via /resolveList)
get_interactors(id, species, limit, required_score)single IDlist[dict] with partner IDs + scores
get_actions(id, species, limit, required_score)single IDlist[dict] with mode (activation/inhibition/binding…)
get_interactions(ids, species, required_score)list of IDslist[dict] pairwise interactions among inputs
search(entity, species, limit, required_score)single entity (any type)dict with resolved_id, interactors, actions
search_batch(entities, species, limit, required_score)list or comma-separated stringdict[str, dict]
summarize(result, entity)search() result + labelcompact text
to_json(result)any resultJSON string

Key Fields

Interactors — stringId_A, stringId_B, preferredName_A, preferredName_B, score, nscore, fscore, pscore, ascore, escore, dscore, tscore

Actions — stringId_A, stringId_B, preferredName_A, preferredName_B, mode (activation / inhibition / binding / catalysis / reaction / expression / ptmod), action, is_directional, a_is_acting, score

Score Channels

AbbrevMeaning
nscoreneighborhood (genomic context)
fscoregene fusion
pscorephylogenetic co-occurrence
ascoreco-expression
escoreexperimental evidence
dscorecurated database evidence
tscoretext mining
scorecombined score (0–1000; 400=medium, 700=high, 900=highest)

Usage

See if __name__ == "__main__" block in 45_STITCH.py for runnable examples covering: free-text name, STITCH CID, batch search, and JSON output.

Data Source

  • Provider: STITCH / STRING Consortium (EMBL, CPR, SIB, KU)
  • Primary URL: http://stitch.embl.de/api
  • Fallback URL: https://string-db.org/api (STITCH data merged into STRING 12+)
  • Auth: None (public API; rate-limited — avoid parallel bulk requests)
  • Species: Default 9606 (Homo sapiens); pass NCBI taxonomy ID for other organisms

Bundled files

The model reads these on demand while the skill is loaded. They are exposed as readable files and are never executed.

Frequently asked questions

What does the Stitch Query AI skill do?

Query the STITCH chemical-protein interaction database. Use whenever the user asks about chemical-protein interactions, drug-target binding, compound action modes, or wants to look up any entity (chemical name, STITCH CID, STRING protein ID) in STITCH.

Why use Stitch Query on TypingMind?

Because you install it once and use it with any model. Stitch Query is plain Markdown rather than provider-specific code, so the same skill runs on GPT-5, Claude, Gemini, Grok, or a local model — and you can switch model mid-chat without it breaking. TypingMind runs on your own API keys, so you pay providers directly instead of a per-seat subscription, and your skills and chats stay in your own storage.

How do I install Stitch Query in TypingMind?

Open Plugins → Skills → Install from GitHub in TypingMind and paste https://github.com/QSong-github/DrugClaw/tree/main/skills/dti/stitch. TypingMind reads its SKILL.md and bundles its files and installs it as a skill you can enable per chat.

Which AI models can use Stitch Query?

Any model you connect in TypingMind. AI skills are plain Markdown instructions rather than provider-specific code, so GPT, Claude, Gemini, Grok, and local models can all load this skill when a request matches it.

How many AI models can I use with Stitch Query?

As many as you like. As long as a model supports skills, you can use Stitch Query with it — GPT, Claude, Gemini, Grok, DeepSeek, Mistral, Llama and more — all on TypingMind with your own API keys.

Is the Stitch Query AI skill free?

It is published on GitHub by QSong-github. Check the repository for licensing terms. You only pay your own AI provider for the tokens you use.

What are AI skills?

An AI skill is a reusable instruction bundle that teaches an AI model how to do one specific task. It follows the open Agent Skills format: a SKILL.md file with a name and description, plus any scripts, templates or reference files the model may need. The model reads the instructions only when your request matches the skill, so an installed skill costs nothing until it is used.

How are AI skills different from plugins or MCP servers?

A plugin or MCP server gives a model new tools to call — code that runs somewhere and returns a result. An AI skill gives the model knowledge and process instead: how to approach a task, which steps to follow, what good output looks like. Skills are plain Markdown, so they need no server, no API key and no runtime, and they work with any model.

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