Drugbank Search

DrugBank Search

Search the complete DrugBank database of drug information including mechanisms of action, interactions, targets, and pharmacology using natural language queries powered by Valyu's semantic search API.

Why This Skill is Powerful

• No API Parameter Parsing: Just pass natural language queries directly - no need to construct complex search parameters
• Semantic Search: Understands the meaning of your query, not just keyword matching
• Full-Text Access: Returns complete drug information including mechanisms, interactions, and targets
• Image Links: Includes molecular structures and data visualizations
• Comprehensive Coverage: Access to all DrugBank drug data

Requirements

1. Node.js 18+ (uses built-in fetch)
2. Valyu API key from https://platform.valyu.ai ($10 free credits)

CRITICAL: Script Path Resolution

The scripts/search commands in this documentation are relative to this skill's installation directory.

Before running any command, locate the script using:

bashCopy code
DRUGBANK_SCRIPT=$(find ~/.claude/plugins/cache -name "search" -path "*/drugbank-search/*/scripts/*" -type f 2>/dev/null | head -1)

Then use the full path for all commands:

bashCopy code
$DRUGBANK_SCRIPT "ACE inhibitors" 15

API Key Setup Flow

When you run a search and receive "setup_required": true, follow this flow:

1. Ask the user for their API key: "To search DrugBank, I need your Valyu API key. Get one free ($10 credits) at https://platform.valyu.ai"

2. Once the user provides the key, run:

   bashCopy code
   scripts/search setup <api-key>
   

3. Retry the original search.

When to Use This Skill

• Comprehensive drug information lookup
• Drug interactions and side effects research
• Target identification and validation
• Mechanism of action studies
• Pharmacokinetics and pharmacodynamics research
• Drug metabolism and adverse event data

Output Format

jsonCopy code
{
  "success": true,
  "type": "drugbank_search",
  "query": "ACE inhibitors",
  "result_count": 10,
  "results": [
    {
      "title": "Drug Name",
      "url": "https://drugbank.com/...",
      "content": "Drug information, mechanism, interactions...",
      "source": "drugbank",
      "relevance_score": 0.95,
      "images": ["https://example.com/structure.png"]
    }
  ],
  "cost": 0.025
}

Processing Results

With jq

bashCopy code
# Get drug names
scripts/search "query" 10 | jq -r '.results[].title'

# Get URLs
scripts/search "query" 10 | jq -r '.results[].url'

# Extract full content
scripts/search "query" 10 | jq -r '.results[].content'

Common Use Cases

Drug Information

bashCopy code
# Find drug details
scripts/search "metformin pharmacokinetics" 50

Drug Interactions

bashCopy code
# Search for interactions
scripts/search "CYP3A4 inhibitor drug interactions" 20

Mechanism Research

bashCopy code
# Find mechanism data
scripts/search "selective serotonin reuptake inhibitors mechanism" 15

Target Identification

bashCopy code
# Search for drug targets
scripts/search "drugs targeting BCR-ABL fusion protein" 25

Error Handling

All commands return JSON with success field:

jsonCopy code
{
  "success": false,
  "error": "Error message"
}

Exit codes:

• 0 - Success
• 1 - Error (check JSON for details)

API Endpoint

• Base URL: https://api.valyu.ai/v1
• Endpoint: /search
• Authentication: X-API-Key header

Architecture

Copy code
scripts/
├── search          # Bash wrapper
└── search.mjs      # Node.js CLI

Direct API calls using Node.js built-in fetch(), zero external dependencies.

Adding to Your Project

If you're building an AI project and want to integrate DrugBank Search directly into your application, use the Valyu SDK:

Python Integration

pythonCopy code
from valyu import Valyu

client = Valyu(api_key="your-api-key")

response = client.search(
    query="your search query here",
    included_sources=["valyu/valyu-drugbank"],
    max_results=20
)

for result in response["results"]:
    print(f"Title: {result['title']}")
    print(f"URL: {result['url']}")
    print(f"Content: {result['content'][:500]}...")

TypeScript Integration

typescriptCopy code
import { Valyu } from "valyu-js";

const client = new Valyu("your-api-key");

const response = await client.search({
  query: "your search query here",
  includedSources: ["valyu/valyu-drugbank"],
  maxResults: 20
});

response.results.forEach((result) => {
  console.log(`Title: ${result.title}`);
  console.log(`URL: ${result.url}`);
  console.log(`Content: ${result.content.substring(0, 500)}...`);
});

See the Valyu docs for full integration examples and SDK reference.